Modeling and Simulation at the Interface of Nonclinical and Early Clinical Drug Development
نویسندگان
چکیده
1Global DMPK, Innovative Medicines, AstraZeneca R&D, Södertälje, Sweden; 2Current affiliation: Merck Research Laboratories, Merck & Co., Inc., Upper Gwynedd, PA, USA; 3European Medicines Agency, London, UK; 4Division of Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands; 5M&S, Merck Sharp & Dohme, Oss, The Netherlands. Correspondence: SAG Visser ([email protected]) Received 2 November 2012; accepted 14 January 2013; advance online publication 27 February 2013. doi:10.1038/psp.2013.3 M&S IN NONCLINICAL AND EARLY CLINICAL DRUG DEVELOPMENT
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